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Research News

ALS Research Roundup Feb.-March 2005
February 01, 2005
Cyclosporine revisited The pharmaceutical company Maas Biolab, of Albuquerque, N.M., and Lund, Sweden, has received Orphan Drug designation from the U.S. Food and Drug Administration to develop
ALS Research Roundup January 2005
January 01, 2005
Gulf War report available online The Research Advisory Committee on Gulf War Veterans’ Illnesses has published online its full report, originally released in September. You can read it at www.
ALS Research Roundup November 2004
November 01, 2004
Cellular transport protein implicated A research group led by Mayana Zatz at the Biosciences Institute of São Paulo (Brazil) University has identified a mutation in a chromosome 20 gene as a likely
ALS Research Roundup October 2004
October 01, 2004
Xaliproden fails in ALS, but hope remains Benjamin Brooks The experimental drug xaliproden has failed to fulfill the promise that earlier trials had hinted at, according to a report in the June
Gene Found for Early-Onset ALS May Shed Light on All ALS Forms
May 01, 2004
An international research group that received significant MDA support has isolated a gene for a rare, slowly progressive, early-onset form of ALS. The disease, called ALS4,has
ALS Research Roundup April 2004
April 01, 2004
VEGF deficiency implicated in second disease A recent MDA-supported study found that a deficiency of a protein called vascular endothelial growth factor (VEGF) is likely
Studies Strengthen Role of Glutamate, Abnormal RNA
April 01, 2004
Jeffrey Rothstein Two recent studies strengthen the role of glutamate, a chemical that normally transmits signals between cells
New Studies Support Roles of Inflammation, Oxidative Stress in ALS
March 01, 2004
Three new studies confirm the roles of two long-suspected factors in the development and perpetuation of ALS. Inflammation is a set of biochemical changes brought about
ALS Research Roundup February 2004
February 01, 2004
Study of new compound open The international pharmaceutical company Novartis has opened a large-scale, dose-finding trial of a compound called TCH346 for treatment of
Naturally Speaking
February 01, 2004
The first phase of a project whose goal is to allow people with ALS and similar conditions to "speak" through a computer in their own
Gulf War Vets More Likely to Get ALS
October 01, 2003
A government-supported research team announced in the Sept. 23 issue of the journal Neurology that having served in southwest Asia during
ALS Doesn’t Masquerade As Lyme Disease, Experts Say
March 01, 2003
Recent items in The ALS Digest, an online publication, have suggested that the tick-borne, bacterial infection known as Lyme disease can
Cognitive Deficits in ALS Are Usually Subtle
March 01, 2003
Benjamin Brooks says it’s important to distinguish between cognitive changes brought about by respiratory abnormalities
Noninvasive Ventilation Prolongs Life if Used Right, MDA Clinic Director Says
September 01, 2002
John Bach Weakness of the muscles that control or influence breathing or swallowing is by far the most serious problem in ALS and requires decisions about whether and how to prolong life. A study in
New Study Explores Connection Between Athletics and ALS
June 01, 2002
Lou Gehrig Catfish Hunter Compared to people with other neurological diseases, people with ALS are more likely to have a history of being athletic and slim, according to a new study from Columbia
Study to Evaluate Speech Synthesis System
June 01, 2002
The Speech Research Laboratory at the Alfred I. duPont Hospital for Children in Wilmington, Del., is seeking people with ALS and their clinicians across the country to participate in a study to
[title]
Bats and Nuts Yield Environmental Clue to ALS on Guam
May 04, 2002
High rates of ALS on Guam may have been caused by the native people’s predilection for eating bats, according to a new theory. Two researchers proposed the theory
Wisconsin ALS Expert Pursuing Viruses, Tamoxifen & Gulf War Exposure
February 16, 2002
Benjamin Brooks directs the MDA/ALS Center at the University of Wisconsin. The center was established in 1987. Benjamin Rix Brooks directs the MDA/ALS Center at the University of Wisconsin
ALS Research Roundup February 2002
February 01, 2002
Unlocking the mysteries of Guamanian ALS After 50 years of research, the cause behind a cluster of ALS among the native people of Guam — the Chamorro — remains a mystery. Some research groups have
People with Myotonic Dystrophy Spur Research Advances
February 01, 2002
The year was 1992, and neurologist John Day had recently moved from the University of California at San Francisco to the University of Minnesota at Minneapolis, where he was to assume the
Stem Cell Therapy Research Taking Several Paths
December 01, 2001
Last year, a research group based at Johns Hopkins University in Baltimore made headlines by injecting stem cells into rodents paralyzed by an ALS-like disease — and restoring movement. Those
Vitamin E Might Help a Little
August 01, 2001
Results of a recent clinical trial suggest that vitamin E may cause a slight delay in the progression of ALS— bittersweet news for people who've followed the hopeful treatment's long history. In the
First Look Suggests Some Benefit from CoQ10
June 01, 2001
In a nine-month study of six people with ALS conducted at the Eleanor & Lou Gehrig MDA/ALS Center at Columbia-Presbyterian Medical Center in New York, investigators found that high-dose, orally
High-Tech Babies, Hands-On Coping
January 31, 2000
Like many first-time parents, Doug and Tina Kurtz of Dayton, Ohio, immersed themselves in books on parenting in preparation for their new arrival. But when their son, Brent, was born with a rare

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