February 01, 2005
Cyclosporine revisited
The pharmaceutical company Maas Biolab, of Albuquerque, N.M., and Lund, Sweden, has received Orphan Drug designation from the U.S. Food and Drug Administration to develop
January 01, 2005
Gulf War report available online
The Research Advisory Committee on Gulf War Veterans’ Illnesses has published online its full report, originally released in September.
You can read it at www.
November 01, 2004
Cellular transport protein implicated
A research group led by Mayana Zatz at the Biosciences Institute of São Paulo (Brazil) University has identified a mutation in a chromosome 20 gene as a likely
October 01, 2004
Xaliproden fails in ALS, but hope remains
Benjamin Brooks
The experimental drug xaliproden has failed to fulfill the promise that earlier trials had hinted at, according to a report in the June
May 01, 2004
An international research group that received significant MDA support has isolated a gene for a rare, slowly progressive, early-onset form of ALS. The disease, called ALS4,has
April 01, 2004
VEGF deficiency implicated in second disease
A recent MDA-supported study found that a deficiency of a protein called vascular endothelial growth factor (VEGF) is likely
April 01, 2004
Jeffrey Rothstein
Two recent studies strengthen the role of glutamate, a chemical that normally transmits signals between cells
March 01, 2004
Three new studies confirm the roles of two long-suspected factors in the development and perpetuation of ALS.
Inflammation is a set of biochemical changes brought about
February 01, 2004
Study of new compound open
The international pharmaceutical company Novartis has opened a large-scale, dose-finding trial of a compound called TCH346 for treatment of
February 01, 2004
The first phase of a project whose goal is to allow people with ALS and similar conditions to "speak" through a computer in their own
October 01, 2003
A government-supported research team announced in the Sept. 23 issue of the journal Neurology that having served in southwest Asia during
March 01, 2003
Recent items in The ALS Digest, an online publication, have suggested that the tick-borne, bacterial infection known as Lyme disease can
March 01, 2003
Benjamin Brooks says it’s important to distinguish between cognitive changes brought about by respiratory abnormalities
September 01, 2002
John Bach
Weakness of the muscles that control or influence breathing or swallowing is by far the most serious problem in ALS and requires decisions about whether and how to prolong life.
A study in
June 01, 2002
Lou Gehrig
Catfish Hunter
Compared to people with other neurological diseases, people with ALS are more likely to have a history of being athletic and slim, according to a new study from Columbia
June 01, 2002
The Speech Research Laboratory at the Alfred I. duPont Hospital for Children in Wilmington, Del., is seeking people with ALS and their clinicians across the country to participate in a study to
May 04, 2002
High rates of ALS on Guam may have been caused by the native people’s predilection for eating bats, according to a new theory.
Two researchers proposed the theory
February 16, 2002
Benjamin Brooks directs the MDA/ALS Center at the University of Wisconsin. The center was established in 1987.
Benjamin Rix Brooks directs the MDA/ALS Center at the University of Wisconsin
February 01, 2002
Unlocking the mysteries of Guamanian ALS
After 50 years of research, the cause behind a cluster of ALS among the native people of Guam — the Chamorro — remains a mystery. Some research groups have
February 01, 2002
The year was 1992, and neurologist John Day had recently moved from the University of California at San Francisco to the University of Minnesota at Minneapolis, where he was to assume the
December 01, 2001
Last year, a research group based at Johns Hopkins University in Baltimore made headlines by injecting stem cells into rodents paralyzed by an ALS-like disease — and restoring movement.
Those
August 01, 2001
Results of a recent clinical trial suggest that vitamin E may cause a slight delay in the progression of ALS— bittersweet news for people who've followed the hopeful treatment's long history.
In the
June 01, 2001
In a nine-month study of six people with ALS conducted at the Eleanor & Lou Gehrig MDA/ALS Center at Columbia-Presbyterian Medical Center in New York, investigators found that high-dose, orally
January 31, 2000
Like many first-time parents, Doug and Tina Kurtz of Dayton, Ohio, immersed themselves in books on parenting in preparation for their new arrival. But when their son, Brent, was born with a rare