September 22, 2009
The first FDA-approved human stem cell trial to treat amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease will be conducted at the Muscular Dystrophy Association ALS Center at Emory
September 22, 2009
A large, multinational study to identify genetic risk factors associated with amyotrophic lateral sclerosis (ALS) has found two DNA sequences on chromosomes 9 and one on chromosome 19 that are
September 01, 2009
It sounds like a good idea, or at least a simple idea:
Human beings have diverse genetic backgrounds and diverse environmental exposures, compared to laboratory mice. It’s much harder to determine
September 01, 2009
Stem cells are a legitimate and exciting area of ALS research, and MDA is actively exploring the potential of these cells.
Stem cells that are too undifferentiated (immature) can be unpredicatable
September 01, 2009
MDA-supported testing is under way to determine whether the commonly used drug pyrimethamine, marketed under the brand name Daraprim, may reduce levels of abnormal SOD1 protein molecules that poison
September 01, 2009
This article reports on research news as of Aug. 31, 2009, on: ALS TDI * Iplex * ALS-PON * emotional symptoms * stem cells
ALS TDI reports quarterly progress
On July 16, 2009, the MDA-supported ALS
August 16, 2009
The pharamaceutical company Avanir has announced positive results for its phase 3 trial to treat unwanted episodes of laughing and crying in patients with ALS and multiple sclerosis using its
August 16, 2009
A new forum for easily accessible scientific information on alternative and off-label (not approved by the Food and Drug Administration) treatments for ALS is now being offered by the World
July 30, 2009
The Richmond, Va., biopharmaceutical company Insmed announced July 27, 2009, that it will not supply its experimental drug Iplex to any new patients with amyotrophic lateral sclerosis (ALS) for the
July 29, 2009
On July 16, 2009, the MDA-supported ALS Therapy Development Institute (ALS TDI) gave its quarterly research update in a Webcast that's now archived on the Institute's site and accessible to all who
July 23, 2009
Update 5/21/12:This study is closed, and results are available at Decision Making About PGD Is Complex, Study Finds. Information about future studies will be posted at PGD: Couples' Decision Making
July 17, 2009
Researchers at the University of Rochester (N.Y.) Wellstone Muscular Dystrophy Cooperative Research Center have identified a compound that has the potential to be developed into a treatment for type
July 13, 2009
A new meta-analysis combining data from 11 studies has found no connection between variations in genes for paraoxonase (PON) enzymes and an increased risk of developing amyotrophic lateral
July 01, 2009
Stem cells — immature cells with the potential to develop into different tissue types — have been heralded as a major advance for developing treatments for a variety of diseases. That’s true for
July 01, 2009
It’s a dance, it’s a dip, it’s an … ALS research network?
SALSA, MDA’s Southeast ALS Alliance, brought together a piquant blend of nearly 30 professionals from 11 hospitals in the Southeastern United
July 01, 2009
Much attention has been paid to gene therapy and stem cell strategies for treating muscle diseases, but several less dramatic strategies also appear to hold potential, especially if used in
July 01, 2009
Recently, media outlets reported a possible link between developing ALS and living near Lake Mascoma in Western New Hampshire.
The Union Leader in New Hampshire and other news outlets indicated that
July 01, 2009
This article presents updates on research, clinical trials and studies in ALS as of June 2009: ceftriaxone, pyrimethamine, tamoxifen, brain-computer interface, gene variants, PLS, spinal cord
July 01, 2009
Story includes research about: Becker muscular dystrophy, Duchenne muscular dystrophy and oculopharyngeal muscular dystrophy.
Success of exon skipping in dogs bodes well for human DMD treatment
June 18, 2009
Recent media reports have raised the question of a possible link between an increased risk of developing amyotrophic lateral sclerosis (ALS) and living near Lake Mascoma in Western New Hampshire.
June 01, 2009
Death of spinal cord neurons in ALS dampens protective mechanism
A vicious cycle of nerve cell damage and loss has been identified as a possible contributor to ALS. Identification of this pathway
June 01, 2009
Biomarkers are a major focus of studies at the ALS Therapy Development Institute.
The 61st annual meeting of the American Academy of Neurology (AAN), held in Seattle April 25-May 2, 2009, included
May 27, 2009
Proteins that keep large molecules from moving freely across blood-vessel walls in the spinal cord appear to be deficient in people with ALS (amyotrophic lateral sclerosis), MDA-supported
May 21, 2009
A variant version of the gene for a protein known as KIFAP3 has been found to increase survival time in people with sporadic (nonfamilial) ALS (amyotrophic lateral sclerosis, or Lou Gehrig's
May 18, 2009
The 61st annual meeting of the American Academy of Neurology (AAN), held in Seattle April 25-May 2, included several ALS-related presentations.
Three concerned identification of biological markers