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Research Digest
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| Mar. 02 |
Prednisone Alternatives Debated in Treatment of Myasthenia Gravis
Rivner MH. Steroid treatment for myasthenia gravis: steroids are overutilized. Muscle Nerve. 2002 Jan;25(1):115-7. Review. No abstract available. [PubMed abstract] |
| Nov. 01 |
MG mystery begins to clear
Hoch W et al. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat Med. 2001 Mar;7(3):365-8. [PubMed abstract] [Quest] |
| July 01 |
New drugs may help in the autoimmune diseases [Quest] Ciafaloni E et al. Mycophenolate mofetil for myasthenia gravis: an open-label pilot study. Neurology. 2000 Jan 9;56(1):97-9. [PubMed abstract] Chaudhry V et al. Mycophenolate mofetil: a safe and promising immunosuppressant in neuromuscular diseases. Neurology. 2000 Jan 9;56(1):94-6. [PubMed abstract] |
| July 01 |
Physical and mental fatigue trouble for those with MG Paul RH et al. Fatigue and its impact on patients with myasthenia gravis. Muscle Nerve. 2000 Sep;23(9):1402-6. [PubMed abstract] [Quest] |
| Nov. 00 |
Vaccine Blocks Development of MG in Dogs, Rats Araga S et al. (2000): A peptide vaccine that prevents experimental autoimmune myasthenia gravis by specifically blocking T cell help. FASEB Journal, 14(1):185-96. [PubMed abstract] [Quest] |
| Dec. 99 |
Gene Defect Causes Acetylcholine Receptors to React to Common Substance Zhou M., et al. (1999): Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes. Proceedings of the National Academy of Sciences, USA, 96: 10466-10471. (MDA-funded) [PubMed abstract] [MDA Technical Summary] |
| Dec. 99 |
Phrenic Nerve Stimulation May Help Determine Cause of Respiratory Failure in Myasthenia Gravis Zifko UA, et al. (1999): Repetitive phrenic nerve stimulation in myasthenic gravis. Neurology, 53:1083-1087. [PubMed abstract] |
| Dec. 99 |
Myasthenic Syndromes Linked to Chromosome 17p Are Caused by Mutations in a Subunit of the Acetylcholine Receptor Middleton L, et al. (1999): Chromosome 17p-linked myasthenia stem from defects in the acteylcholine receptor eta-subunit. Neurology, 53:1076-1082. (MDA funded) [PubMed abstract] |
| Dec. 99 |
Nasal Spray Utilizing Pieces of the Actylcholine Receptor May Be Therapy for Myasthenia Gravis Barchan D, et al. (1999): Antigen-specific modulation of experimental myasthenia gravis: Nasal tolerization with recombinant fragments of the human acetylcholine receptor alpha-subunit. Proceedings of the National Academy of Sciences, USA, 96(14):8086-8091. (MDA funded) [PubMed abstract] [Quest] |
| Sept. 99 |
Neurofilament Protein in Thymoma May be Trigger for MG Shultz, A. et al. (1999): Neurofilament is an autoantigenic sdeterminant in myasthenia gravis. Annals of Neurology, 46:167-175. [PubMed abstract] |
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