July 27, 2005

Study of NIPPV, Nutrition In ALS Under Way

A National Institutes of Health-supported study of strategies for noninvasive (non-tracheostomy) positive pressure ventilation (NIPPV) and nutritional support via a feeding tube is under way at 11 U.S. sites.

The study, which hopes to include 220 adults with ALS, seeks to develop reliable indicators of early respiratory or nutritional deficits.

The investigative group, headed by Edward Kasarskis at the University of Kentucky in Lexington, will estimate participants’ caloric requirements at different ALS stages, identify methods to detect early respiratory dysfunction, and see what factors influence how well people tolerate NIPPV.

For information, contact Megan Thompson in Lexington at (859) 323-8509 or megant@uky.edu.